Throughout the lifecycle of an illicit synthetic drug there are a number of individuals or institutions in a position to reduce supply. This project aims to identify concrete examples of law enforcement agencies harnessing external institutions (public, private and non-profit) in furtherance of amphetamine and other illicit synthetic drug control, and to analyse the strengths and weaknesses of each. The research has focused on strategies adopted by law enforcement agencies overseas, and involved fieldwork in Asia, Europe and the United States. The study discusses international and Australian chemical diversion control initiatives and the challenges of diversion control and supply reduction partnerships, and examines various models adopted by the United Kingdom, the Netherlands and the United States to prevent the diversion of necessary chemicals and equipment into the manufacture of illicit synthetic drugs. The study concludes that law enforcement can harness the resources of other organisations in the public and private sectors through a range of mechanisms both mandatory and voluntary, and summarises a number of best practice principles for supply reduction partnerships which have been distilled from the case studies. (Executive summary, edited)